Composition
Active Hydrocortisone (microfine) 1% w/w, clotrimazole 1% w/w. Inactive Cetomacrogol 1000, glycerin, cetostearyl alcohol, light liquid paraffin, soft white paraffin, propylene glycol, purified water, chlorocresol 0.2% as a preservative. The cream (nonionic) is lanolin free and does not contain parabens preservatives.
Description
Hydrocortisone. Hydrocortisone Chemical name: 11β, 17α, 21-trihydroxypregn-4-ene-3, 20-dione. Molecular formula: C21H30O5. MW: 362.5, CAS: 50-23-7. Hydrocortisone is an odourless, white or almost white crystalline powder. It is practically insoluble in water, sparingly soluble in acetone and in alcohol, slightly soluble in methylene chloride, very slightly soluble in ether.
Clotrimazole Chemical name: 1-(o-chloro-αα-diphenylbenzyl) imidazole. Molecular formula: C22H17CIN2. MW: 344.84. CAS: 23593-75-1. Melting point: 141 to 145°C. It is a colourless, crystalline, weakly alkaline substance, soluble in acetone, chloroform and ethanol and practically insoluble in water. It forms stable salts with both organic and inorganic acids. It is not photosensitive but is slightly hygroscopic, and may be hydrolysed in acid media. The structural formula is given below:
Dual action
Hydrozole
1. eases the inflammation
Hydrocortisone acts to relieve the inflammation caused by a fungal infection, to reduce the redness, ease the irritation and stop that maddening itch.
2. tackles the infection
Clotrimazole is the antifungal ingredient that fights the infection itself by getting rid of the fungi and stopping it spreading any further.
What does
it all mean?
Is tinea the same as athlete’s foot? Is jock itch a form of ringworm, or is that something else? Our Glossary clears up the confusion...
